Wikipedista:Julie Vacková/editujte s odvahou: Porovnání verzí

'''Macrophage polarization''' is a proces when macrophages express different functional programs in response to microenvironmental signals.<ref>Mantovani, Alberto, et al. "Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes." Trends in immunology 23.11 (2002): 549-555.</ref> There are a lot of functional states of macrophage polarization and they can be fully polarized and acquire specific phenotype like M1 or M2. <ref>Hamilton, T. A. (2014). "Myeloid Colony Stimulating Factors as Regulators of Macrophage Polarization." Frontiers in Immunology</ref> This specific phenotypes depends on the and the tissue and specific microenvironment where are macrophages.<ref>Lawrence, Toby, and Gioacchino Natoli. "Transcriptional regulation of macrophage polarization: enabling diversity with identity." Nature reviews immunology 11.11 (2011): 750-761.</ref>